Physiological hair loss is a natural phenomenon that occurs cyclically. In place of the hair that falls out, a new one grows back. This is the so-called hair cycle, which, on average, during a person's life is repeated from 20 to 40 times. There are about 100,000 hairs on the scalp, and the lifespan of the hair is on average 4 to 7 years. Hair loss up to 80 per day is taken as the norm. From the above data, it follows that a statistical person should have full head hair until old age.

In practice, at different ages, we meet with excessive hair loss and baldness. This is influenced by endogenous and exogenous factors. The main problem is hair loss caused by exogenous factors; this affects about 70% of people. Endogenous factors are mainly genetically determined hormonal and metabolic disorders. We encounter exogenous factors in everyday life, including, among others: medicines, chemicals, inadequate diet, cosmetics, atmospheric pollution, solar radiation, and states of emotional tension. They cause damage to varying degrees of hair follicles, which leads to excessive hair loss and baldness. In people with a genetically determined tendency to baldness, the action of exogenous factors contributes to the severity of the disease.

The toxic effect of the above-mentioned factors consists in releasing an excessive amount of free oxygen radicals in the body. This leads to so-called oxidative stress.